LDH (Lactate Dehydrogenase)

A non-specific but sensitive marker of tissue damage and tumour burden.

What it is

LDH is an enzyme found in nearly every cell. When cells are damaged or die — from any cause — LDH is released into the bloodstream. It is a sensitive but non-specific marker.

Why it matters

In oncology, LDH is a prognostic marker correlated with tumour burden and aggressive disease. Falling LDH during treatment suggests cells are responding. It is also elevated by haemolysis, liver disease, and muscle injury.

How to test

Standard blood panel. Haemolysed (destroyed) blood samples give falsely elevated readings — ensure prompt processing.

This information is for educational purposes only. Always discuss testing and interpretation of results with your care team.

Optimal range

120–240 U/L

normal range (lab-dependent)

Above 250 U/L

elevated — interpret in clinical context

How often

Every oncology panel, or every 6–12 weeks.