MPV (Mean Platelet Volume)

Average platelet size — larger platelets are more active.

What it is

MPV is the average size of platelets. Larger platelets are younger, more metabolically active, and better at clotting. Rising MPV after chemotherapy-induced thrombocytopenia signals bone marrow recovery.

Why it matters

A rising MPV alongside recovering PLT count is a reassuring sign of bone marrow regeneration. Conversely, low MPV with low PLT may indicate suppressed marrow rather than consumption. It adds nuance to interpreting platelet counts.

How to test

Full blood count.

This information is for educational purposes only. Always discuss testing and interpretation of results with your care team.

Optimal range

7.5–12.5 fL.

How often

Each blood count panel.